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Brief Title: Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects
Official Title: Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects
Study ID: NCT00762801
Brief Summary: RLIP76 (Ral binding protein1) is a 76 kDa splice variant protein encoded by the human gene (RALBP1, 18p11.22). It is a multifunctional modular protein found ubiquitously from Drosophila to humans, in cells ranging from red blood cells to endothelial cells of the brain. Its expression more predominant in breast, heart, liver and less so in colon and brain parenchyma.
Detailed Description: RLIP76 is shown to be over expressed in a variety of cancer cells. However, no study has yet been done on its expression on normal cells. The studies proposed in this project will study the expression of RLIP76 in blood cells of healthy human subjects in the population of North Texas region.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
University of North Texas Health Science Center, Fort Worth, Texas, United States
University of North Texas Health Science Center, Fort Worth, Texas, United States
Name: Sanjay Awasthi, MD
Affiliation: University of North Texas Health Science Center
Role: PRINCIPAL_INVESTIGATOR