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Brief Title: ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Official Title: A Phase II/III Study of ICP-248 in Combination With Orelabrutinib in Patients With Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Study ID: NCT06378138
Brief Summary: Evaluate the safety, tolerability and pharmacokinetics of ICP-248 in Combination with Orelabrutinib in Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Peking University Third Hospital, Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
Xinqiao Hospital, the Second Affiliated Hospital of Army Military Medical University, Chongqing, Chongqing, China
Fujian Medical University Union Hospital, Fuzhou, Fujian, China
The First Affiliated Hospital of Xiamen University, Xiamen, Fujian, China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
Nanyang City Center Hospital, Nanyang, Henan, China
Henan Provincial People's Hospital, Zhengzhou, Henan, China
Henan Cancer Hospital, Zhenzhou, Henan, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Hunan Cancer Hospital, Changsha, Hunan, China
Jiangsu Province Hospital, Nanjing, Jiangsu, China
The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
Bethune First Hospital of Jilin University, Changchun, Jilin, China
The Second Hospital of Dalian Medical University, Dalian, Liaoning, China
Shengjing Hospital affiliated to China Medical University, Shenyang, Liaoning, China
Shandong Cancer Hospital, Jinan, Shandong, China
Linyi City Cancer Hospital, Linyi, Shandong, China
Huashan Hospital, Shanghai, Shanghai, China
The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shanxi, China
Sichuan Provincial People's Hospital, Chengdu, Sichuan, China
Yibin Second People's Hospital, Yibin, Sichuan, China
Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China
The Affiliated Cancer Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China
The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
The First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China