Spots Global Cancer Trial Database for A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies
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Trial Identification
Brief Title: A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies
Official Title: A Long-term Follow-up Study of Subjects With Malignancies Treated With CRISPR CAR T Cellular Therapies
Study ID: NCT06208878
Interventions
Study Description
Brief Summary: This study will evaluate the long-term safety and efficacy of CRISPR CAR T cellular therapies
Detailed Description: All subjects with hematological and solid malignancies who are enrolled in a parent study and were exposed to allogeneic CRISPR CAR T cellular therapy will be asked to participate in this long-term follow-up (LTFU) study. Subjects who have completed the parent study for the protocol-defined duration, or who have discontinued the parent study early, or who are in secondary follow-up (follow up of subjects with progressive disease or who receive a subsequent line of anticancer therapy) in the parent study may enroll in this LTFU study. This will allow for collection of long-term efficacy data (as applicable) and safety data up to 15 years post-treatment with CRISPR CAR T cellular therapies.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
City of Hope, Duarte, California, United States
Cedars Sinai, Los Angeles, California, United States
Yale New Haven Hospital, New Haven, Connecticut, United States
University of Kansas, Westwood, Kansas, United States
University of Minnesota, Minneapolis, Minnesota, United States
Washington University Saint Louis, Saint Louis, Missouri, United States
Montefiore Medical Center, Bronx, New York, United States
Oregon Health and Science University, Portland, Oregon, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
MD Anderson Cancer Center, Houston, Texas, United States
Methodist Hospital-Sarah Cannon, San Antonio, Texas, United States
University of Utah-Huntsman Cancer Institute, Salt Lake City, Utah, United States
Sir Charles Gairdner, Nedlands, , Australia
Contact Details
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