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Spots Global Cancer Trial Database for URMC Related Haplo-identical Donor BMT

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Trial Identification

Brief Title: URMC Related Haplo-identical Donor BMT

Official Title: Haploidentical Donor Hematopoietic Stem Cell Transplantation

Study ID: NCT02660281

Study Description

Brief Summary: This study will be a single-center treatment protocol, designed to validate the process of related donor haploidentical-SCT at the Wilmot Cancer Institute Blood and Marrow Transplant Unit.

Detailed Description: This study will be a single-center treatment protocol with five possible preparative regimens, designed to validate the process of related donor haploidentical-SCT at the Wilmot Cancer Institute Blood and Marrow Transplant Unit. Enrolled patients will receive chemotherapy +/- radiation as a pre-transplant conditioning regimen. Patients will then receive haploidentical stem cells, either bone marrow or mobilized peripheral blood, followed by GvHD prophylaxis that will include cyclophosphamide. Multiple data points will be collected prior to, during, and following transplantation to ensure safety of the process and to evaluate the stated objectives.

Keywords

Eligibility

Minimum Age: 6 Months

Eligible Ages: CHILD, ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Wilmot Cancer Institute, Rochester, New York, United States

Contact Details

Name: Jeffrey Andolina, MD

Affiliation: Wilmot Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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