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Brief Title: A Study of Nemtabrutinib (MK-1026) in China Participants With Relapsed or Refractory Hematologic Malignancies (MK-1026-005)
Official Title: A Phase 1 Clinical Study to Investigate the Safety, Pharmacokinetics and Efficacy of MK-1026 in China Participants With Relapsed or Refractory Hematologic Malignancies
Study ID: NCT05347225
Brief Summary: The purpose of this study is to evaluate the safety, pharmacokinetics (PK) and preliminary efficacy of oral nemtabrutinib in Chinese participants at least 18 years of age who have Relapsed/Refractory hematologic malignancies.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Guangdong Provincial People's Hospital-hematology department ( Site 1002), Guangzhou, Guangdong, China
SUN YAT-SEN UNIVERSITY CANCER CENTRE-Internal medicine ( Site 1007), Guangzhou, Guangdong, China
Henan Cancer Hospital-hematology department ( Site 1003), Zhengzhou, Henan, China
Hunan Cancer Hospital ( Site 1004), Changsha, Hunan, China
Institute of hematology&blood disease hospital-Hematology ( Site 1001), Tianjin, Tianjin, China
Name: Medical Director
Affiliation: Merck Sharp & Dohme LLC
Role: STUDY_DIRECTOR