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Brief Title: Etoposide+Cytarabine+PEG-rhG-CSF for Hematopoietic Stem Cell Mobilization in Patients With Hematological Malignancies
Official Title: Prospective, Single-arm, Multicenter Exploratory Clinical Study of the Combination of Etoposide, Cytarabine and PEG-rhG-CSF (EAP Regimen) on Hematopoietic Stem Cell Mobilization in Poor Mobilization Patients With Hematological Malignancies
Study ID: NCT05510089
Brief Summary: This is a single-arm, multicenter, exploratory clinical study to evaluate the safety and efficacy of the combination of etoposide, cytarabine and PEG-rhG-CSF (EAP regimen) on hematopoietic stem cell mobilization in poor mobilization patients with hematological malignancies. All eligible patients will receive EAP regimen treatment, then the number of CD34+ cells and white blood cells will be monitoring. When the collection standard is met, hematopoietic stem cell collection will be started.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Dongyang People's Hospital, Dongyang, Zhejiang, China
Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Huzhou central hospital, Huzhou, Zhejiang, China
Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China
Jinhua People's Hospital, Jinhua, Zhejiang, China
Lishui Municipal Central Hospital, Lishui, Zhejiang, China
The Affiliated People's Hospital of Ningbo University., Ningbo, Zhejiang, China
Shaoxing People's Hospital, Shaoxing Hospital of Zhejiang University, Shaoxing, Zhejiang, China
Shaoxing Second Hospital, Shaoxing, Zhejiang, China
Taizhou Central Hospital, Taizhou, Zhejiang, China
Taizhou Hospital of Zhejiang Province, Taizhou, Zhejiang, China
Name: Ying Lu
Affiliation: The Affiliated People's Hospital of Ningbo University
Role: PRINCIPAL_INVESTIGATOR