Spots Global Cancer Trial Database for Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma
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Trial Identification
Brief Title: Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma
Official Title: Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma
Study ID: NCT01765231
Conditions
Study Description
Brief Summary: The purpose of this study is to identify the effect of prophylactic entecavir in HBsAg Negative/HBcAb Positive/hepatitis B virus DNA Negative patients with lymphoma.
Detailed Description: The purpose of this study is to identify the effect of prophylactic entecavir in HBsAg Negative/HBcAb Positive/hepatitis B virus DNA Negative patients with lymphoma are randomized into entecavir prophylaxis group or observation group. In entecavir prophylaxis group, entecavir 0.5 mg/day orally is initiate on day 1 of the first course of antitumor therapy, and will be continued until at least 6 months after completion of antitumor therapy. In observation group, entecavir 0.5mg daily will be prescribed for patients with hepatitis B virus reactivation.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Peking University Cancer Hospital & Institute, Beijing, Beijing, China
307 Hospital of the Chinese People's Liberation Army, Beijing, Beijing, China
309 Hospital of the Chinese People's Liberation Army, Beijing, Beijing, China
Aerospace Central Hospital, Beijing, Beijing, China
Air Force General Hospital of the Chinese People's Liberation Army, Beijing, Beijing, China
Beijing Hospital, Beijing, Beijing, China
Cancer Institute & Hospital, Chinese Academy of Medical Sciences, Beijing, Beijing, China
First Hospital affiliated to General Hospital of the Chinese People's Liberation Army, Beijing, Beijing, China
General Hospital of Chinese People's Liberation Army, Beijing, Beijing, China
Peking Union Medical College Hospital, Beijing, Beijing, China
Peking University First Hospital, Beijing, Beijing, China
Peking University People's Hospital, Beijing, Beijing, China
Peking University Third Hospital, Beijing, Beijing, China
Contact Details
Name: Jun Zhu
Affiliation: Peking University Cancer Hospital & Institute
Role: PRINCIPAL_INVESTIGATOR
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