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Brief Title: Direct Acting Antiviral-Post Authorization Safety Study
Official Title: DAA-PASS: A Post-Authorisation Safety Study of Early Recurrence of Hepatocellular Carcinoma in HCV-Infected Patients After Direct-Acting Antiviral Therapy
Study ID: NCT03707080
Brief Summary: This is an independent optional sub-study parallel to TARGET-HCC (NCT02954094). The purpose of Direct-Acting Antiviral-Post Authorization Safety Study (DAA-PASS) is to investigate the impact of exposure to direct-acting antivirals (DAAs) on early recurrence of hepatocellular carcinoma (HCC) in hepatitis C virus (HCV)-infected patients following successful HCC treatment interventions.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Banner University Medical Center, Phoenix, Arizona, United States
University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
Norris Comprehensive Cancer Center, Los Angeles, California, United States
Stanford University, Palo Alto, California, United States
California Liver Research Institute, Pasadena, California, United States
University of California - Davis Clinical Trials, Sacramento, California, United States
University of California - San Francisco, San Francisco, California, United States
Georgetown University, Washington, District of Columbia, United States
Gastro Florida, Clearwater, Florida, United States
University of Florida Hepatology Research at CTRB, Gainesville, Florida, United States
University of Florida - Health Gastroenerology, Jacksonville, Florida, United States
Schiff Center for Liver Diseases, Miami, Florida, United States
Tampa General Medical Group, Tampa, Florida, United States
Piedmont Atlanta Hospital, Atlanta, Georgia, United States
Emory University Hospital, Atlanta, Georgia, United States
Northwestern University Division of Gastroenterology and Hepatology, Chicago, Illinois, United States
Rush University Medical Center, Chicago, Illinois, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Tulane University School of Medicine, New Orleans, Louisiana, United States
Mercy Medical Center, Baltimore, Maryland, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
University of Michigan, Ann Arbor, Michigan, United States
Henry Ford Health System, Detroit, Michigan, United States
Mayo Clinic, Rochester, Minnesota, United States
Southern Therapy and Advanced Research LLC, Jackson, Mississippi, United States
Saint Louis University, Saint Louis, Missouri, United States
Rutgers-Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States
Northwell Health - Center for Liver Disease, Manhasset, New York, United States
New York University Langone Health, New York, New York, United States
Weill Cornell Medical College, New York, New York, United States
Columbia University Medical Center, New York, New York, United States
Carolinas HealthCare System Center for Liver Disease, Charlotte, North Carolina, United States
Providence Health & Services Cancer Clinical Trials, Portland, Oregon, United States
Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Vanderbilt University Medical Center - GI Research Office, Nashville, Tennessee, United States
Clinical Research Institute@ Methodist Dallas Medical Center, Dallas, Texas, United States
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Baylor Scott & White All Saints, Fort Worth, Texas, United States
Research Specialists of Texas, Houston, Texas, United States
Research Specialists of Texas, Houston, Texas, United States
University of Virginia Transplant Center, Charlottesville, Virginia, United States
Bon Secours Liver Institute of Virginia, Richmond, Virginia, United States
Virginia Commonwealth University, Richmond, Virginia, United States
Harborview Medical Center, Seattle, Washington, United States
Wenatchee Valley Hospital & Clinics, Wenatchee, Washington, United States
CHU de Nice - HĂ´pital L'Archet 2, Nice, , France
HĂ´pitaux Universitaires Paris Centre, Paris, , France
CharitÊ - Universitätsmedizin Berlin, Berlin, , Germany
Universitätsklinikum Frankfurt, Frankfurt, , Germany
Universitätsklinikum Leipzig, Leipzig, , Germany
Universitätsklinikum Magdeburg, Magdeburg, , Germany
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, , Italy
A.O.U.P. di Palermo, Palermo, , Italy
Humanitas Mirasole IRCCS, Rozzano, , Italy
IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, , Italy
Hospital Puerta de Hierro Majadahonda, Madrid, , Spain
ClĂnica Universidad de Navarra, Pamplona, , Spain
Hospital Universitario Marques de Valdecilla, Santander, , Spain
Hospital Universitario Virgen del RocĂo, Sevilla, , Spain
Hospital Universitario Politècnic La Fe, Valencia, , Spain