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Brief Title: First Line Hepato Cellular Carcinoma (HCC)
Official Title: A Randomized, Double-blind, Multi-center Phase III Study of Brivanib Versus Sorafenib as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
Study ID: NCT00858871
Brief Summary: The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Mayo Clinic Arizona, Scottsdale, Arizona, United States
Univ Of Ark For Med Sci, Little Rock, Arkansas, United States
Agajanian Institute Of Hematology And Oncology, Downey, California, United States
Sharp Clinical Oncology Research, San Diego, California, United States
Va Ct Healthcare System, West Haven, Connecticut, United States
Medical Specialists Of Palm Beaches, Lake Worth, Florida, United States
James Graham Brown Cancer Center, Louisville, Kentucky, United States
3912 Taubman Center, Ann Arbor, Michigan, United States
Karmanos Cancer Institute, Detroit, Michigan, United States
Thomas Jefferson Univ., Philadelphia, Pennsylvania, United States
Mcguire Dvamc, Richmond, Virginia, United States
University Of Wisconsin, Madison, Wisconsin, United States
Local Institution, Caba, Buenos Aires, Argentina
Local Institution, Capital Federal, Buenos Aires, Argentina
Local Institution, Rosario, Santa Fe, Argentina
Local Institution, Buenos Aires, , Argentina
Local Institution, Camperdown, New South Wales, Australia
Local Institution, Concord, New South Wales, Australia
Local Institution, Westmead Nsw, New South Wales, Australia
Local Institution, Parkville, Victoria, Australia
Local Institution, Prahan, Victoria, Australia
Local Institution, Liege, , Belgium
Local Institution, Salvador - Ba, Bahia, Brazil
Local Institution, Salvador, Bahia, Brazil
Local Institution, Fortaleza, Ceara, Brazil
Local Institution, Goiania, Goias, Brazil
Local Institution, Divinopolis, Minas Gerais, Brazil
Local Institution, Curitiba, Parana, Brazil
Local Institution, Porto Alegre, Rio Grande do Sul, Brazil
Local Institution, Porto Alegre, Rio Grande Do Sul, Brazil
Local Institution, Porto Alegre, Rio Grande Do Sul, Brazil
Local Institution, Barretos, Sao Paulo, Brazil
Local Institution, Jau, Sao Paulo, Brazil
Local Institution, Sao Paulo, , Brazil
Local Institution, Calgary, Alberta, Canada
Local Institution, Vancouver, British Columbia, Canada
Local Institution, London, Ontario, Canada
Local Institution, Montreal, Quebec, Canada
Local Institution, Beijing, Beijing, China
Local Institution, Beijing, Beijing, China
Local Institution, Beijing, Beijing, China
Local Institution, Chongqing, Chongqing, China
Local Institution, Guangzhou, Guangdong, China
Local Institution, Guanzhou, Guangdong, China
Local Institution, Nanning, Guangxi, China
Local Institution, Wuhan, Hubei, China
Local Institution, Changsha, Hunan, China
Local Institution, Changzhou, Jiangsu, China
Local Institution, Nanjing, Jiangsu, China
Local Institution, Nanjing, Jiangsu, China
Local Institution, Nanjing, Jiangsu, China
Local Institution, Suzhou, Jiangsu, China
Local Institution, Dalian, Liaoning, China
Local Institution, Xi An, Shaanxi, China
Local Institution, Shanghai, Shanghai, China
Local Institution, Chengdu, Sichuan, China
Local Institution, Hangzhou, Zhejiang, China
Local Institution, Brno, , Czech Republic
Local Institution, Prague 5, , Czech Republic
Local Institution, Praha 2, , Czech Republic
Local Institution, Bordeaux, , France
Local Institution, Clichy Cedex, , France
Local Institution, Creteil Cedex, , France
Local Institution, Grenoble Cedex 09, , France
Local Institution, Lille, , France
Local Institution, Lyon Cedex 04, , France
Local Institution, Marseille Cedex 05, , France
Local Institution, Marseille Cedex 9, , France
Local Institution, Paris, , France
Local Institution, Paris, , France
Local Institution, Paris, , France
Local Institution, Rennes, , France
Local Institution, Vandoeuvre Cedex, , France
Local Institution, Berlin, , Germany
Local Institution, Halle, , Germany
Local Institution, Hamburg, , Germany
Local Institution, Magdeburg, , Germany
Local Institution, Ulm, , Germany
Local Institution, Hong Kong, , Hong Kong
Local Institution, Shatin, , Hong Kong
Local Institution, Hyderabad, Andhra Pradesh, India
Local Institution, Kochi, Kerala, India
Local Institution, Trivandrum, Kerala, India
Local Institution, Pune, Maharashtra, India
Local Institution, Ahmedabad, , India
Local Institution, Chennai, , India
Local Institution, Coimbatore, , India
Local Institution, Hyderabad, , India
Local Institution, Kolkata, , India
Local Institution, Kolkata, , India
Local Institution, Mumbai, , India
Local Institution, Mumbai, , India
Local Institution, New Delhi, , India
Local Institution, Milano, , Italy
Local Institution, Milano, , Italy
Local Institution, Napoli, , Italy
Local Institution, Pisa, , Italy
Local Institution, Roma, , Italy
Local Institution, Torrette -Ancona, , Italy
Local Institution, Kashiwa-shi, Chiba, Japan
Local Institution, Sapporo-shi, Hokkaido, Japan
Local Institution, Kanazawa-Shi, Ishikawa, Japan
Local Institution, Kawasaki-shi, Kanagawa, Japan
Local Institution, Yokohama, Kanagawa, Japan
Local Institution, Tsu-shi, MIE, Japan
Local Institution, Okayama-shi, Okayama, Japan
Local Institution, Higashinari-ku, Osaka, Japan
Local Institution, Osaka-Sayama City, Osaka, Japan
Local Institution, Osaka-shi, Osaka, Japan
Local Institution, Osaka-shi, Osaka, Japan
Local Institution, Osaka-shi, Osaka, Japan
Local Institution, Sunto-gun, Shizuoka, Japan
Local Institution, Chuo-Ku, Tokyo, Japan
Local Institution, Minato-ku, Tokyo, Japan
Local Institution, Musashino-shi, Tokyo, Japan
Local Institution, Shimonoseki-shi, Yamaguchi, Japan
Local Institution, Nishinomiya-shi, , Japan
Local Institution, Busan, , Korea, Republic of
Local Institution, Daegu, , Korea, Republic of
Local Institution, Gyeonggi-do, , Korea, Republic of
Local Institution, Kyunggi-do, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution, Seoul, , Korea, Republic of
Local Institution, D.f., Distrito Federal, Mexico
Local Institution, D.f., Distrito Federal, Mexico
Local Institution, Mexico City, Distrito Federal, Mexico
Local Institution, Tlalpan, Distrito Federal, Mexico
Local Institution, Monterrey, Nuevo Leon, Mexico
Local Institution, Aguascalientes, , Mexico
Local Institution, Distrito Federal, , Mexico
Local Institution, Gdansk, , Poland
Local Institution, Gliwice, , Poland
Local Institution, Krakow, , Poland
Local Institution, Warszawa, , Poland
Local Institution, San Juan, , Puerto Rico
Local Institution, Moscow, , Russian Federation
Local Institution, Moscow, , Russian Federation
Local Institution, Moscow, , Russian Federation
Local Institution, Moscow, , Russian Federation
Local Institution, Pretoria, Gauteng, South Africa
Local Institution, Durban, Kwa Zulu Natal, South Africa
Local Institution, Cape Town, Western Cape, South Africa
Local Institution, Observatory, Cape Town, Western Cape, South Africa
Local Institution, Rondebosch, Western Cape, South Africa
Local Institution, Santiago De Compostela, A Coruna, Spain
Local Institution, Alicante, , Spain
Local Institution, Barcelona, , Spain
Local Institution, Stockholm, , Sweden
Local Institution, Uppsala, , Sweden
Local Institution, Changhua, , Taiwan
Local Institution, Kaohsiung, , Taiwan
Local Institution, Taichung, , Taiwan
Local Institution, Tainan R.O.C., , Taiwan
Local Institution, Taipei, , Taiwan
Local Institution, Taipei, , Taiwan
Local Institution, Taoyuan, , Taiwan
Local Institution, Bangkok, , Thailand
Local Institution, Bangkok, , Thailand
Local Institution, Ankara, , Turkey
Local Institution, Antalya, , Turkey
Local Institution, Istanbul, , Turkey
Local Institution, Izmir, , Turkey
Local Institution, Kayseri, , Turkey
Local Institution, Bristol, Avon, United Kingdom
Local Institution, London, Greater London, United Kingdom
Local Institution, London, Greater London, United Kingdom
Local Institution, London, Greater London, United Kingdom
Local Institution, Manchester, Greater Manchester, United Kingdom
Local Institution, Birmingham, West Midlands, United Kingdom
Local Institution, Leeds, Yorkshire, United Kingdom
Name: Bristol-Myers Squibb
Affiliation: Bristol-Myers Squibb
Role: STUDY_DIRECTOR