Spots Global Cancer Trial Database for Benefit of the Use of 3D Models and Tools in Hepatectomy Planning for Hepatocarcinomas
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Trial Identification
Brief Title: Benefit of the Use of 3D Models and Tools in Hepatectomy Planning for Hepatocarcinomas
Official Title: Multicentric Study Determining the Benefit of the Use of 3D Models and Tools in Hepatectomy Planning for Hepatocarcinomas
Study ID: NCT03382327
Conditions
Interventions
Study Description
Brief Summary: The aim of this study is to assess the benefit of 3D models in the planning of hepatic resection by comparing the changes in the surgical plan based on the analysis of conventional preoperative images (CT-scan and MRI), compared to the surgical plan based on the analysis of 3D reconstruction.
Detailed Description: The detailed anatomical description of the liver described by Couinaud in 1954 is the basis for hepatic surgery. Surgical resection is the approach leading to the best survival rate in case of liver cancer. In hepatocarcinomas, systematic removal of the infected liver segment is considered the most effective technique to eliminate tumour, potential satellite nodules and avoid vascular spread. Resectability rate highly depends on the analysis of preoperative images. However, in 20% of cases, there are modifications compared with the initial surgical plan leading to an increase in morbidity rate. In 2002, Couinaud highlighted the difficulty of identifying portal pedicles, especially because of anatomical variations, and recommended the use of a three-dimensional reconstruction from images provided by a helical scanner. The hypothesis of the study is that 3D models would improve surgical planning leading to a decrease in intra-operative adjustments and mortality. The aim of this multicentric, prospective study is to assess the benefit of 3D models in the surgical management of hepatocarcinomas, more specifically in the detailed analysis of 3D vascular structures and in the surgery planning with resection merges evaluation. The validation of this virtual method will be built on the comparison of the surgical plan based on the analysis of conventional preoperative images (CT-scan and MRI) and the surgical plan based on the analysis of 3D reconstruction.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Service de Chirurgie Digestive - Hôpital Beaujon, Clichy, , France
Hôpital Henri Mondor - Service de Chirurgie Digestive et Hépatobiliaire -, Créteil, , France
Service de Chirurgie Digestive et Transplantation - Hôpital Claude Huriez, Lille, , France
Service de Chirurgie Digestive et Transplantation Hépatique - Hôpital universitaire de la Croix-Rousse, Lyon, , France
Service de Chirurgie Digestive - CH Emile Muller, Mulhouse, , France
Chirurgie Viscérale et Digestive - Polyclinique de Gentilly, Nancy, , France
Chirurgie Digestive, Hépato-bilio-pancréatique et Transplantation - La Pitié Sâlpêtrière, Paris, , France
Service de Chirurgie Digestive - CHU Robert Debré, Reims, , France
Service de Chirurgie Digestive Hôpital Charles Nicolle - CHU Rouen, Rouen, , France
Institut de Chirurgie Viscérale - Clinique de l'Orangerie, Strasbourg, , France
Service de Chirurgie Digestive et Endocrinienne - Nouvel Hôpital Civil, Strasbourg, , France
Centre Hépato-Biliaire - Hôpital Paul Brousse, Villejuif, , France
Contact Details
Name: Patrick Pessaux, MD, PhD
Affiliation: Service de Chirurgie Digestive et Endocrinienne - Nouvel Hôpital Civil - Strasbourg
Role: PRINCIPAL_INVESTIGATOR
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