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Spots Global Cancer Trial Database for RALPPS Venus ALPPS for Hepatocellular Carcinoma

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Trial Identification

Brief Title: RALPPS Venus ALPPS for Hepatocellular Carcinoma

Official Title: A Prospective Randomized Controlled Trial of Radio-frequency Assisted ALPPS(RALPPS)and Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy(ALPPS)in the Treatment of Hepatocellular Carcinoma.

Study ID: NCT02299843

Interventions

RALPPS
ALPPS

Study Description

Brief Summary: Currently,the "ALPPS" (associating liver partition with portal vein ligation for staged hepatectomy) procedure which enables the rapid growth of the future liver remnant and extends surgical indication to patients with mid-advanced stage hepatocellular carcinoma becomes a research hot spot. However, the procedure has a high morbidity and mortality rate.Using radio-frequency ablation instead of in-situ split of liver to avoid forming a coagulation band in stage I will reduce the incidence of complications(bile leakage, abdominal infection,hemorrhage e.t.) The investigators named this technique as Radio-frequency Assisted Liver Partition with Portal vein ligation for staged hepatectomy (RALPPS).Investigators hypothesized that the RALPPS might result in lower morbidity and mortality rate than ALPPS in the treatment of hepatocellular carcinoma . This Prospective Randomized Controlled Trial is on the Safety and Efficacy of radio-frequency assisted liver partition with portal vein ligation for staged hepatectomy for hepatocellular carcinoma.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Institute of hepatobiliary surgery,Southwest Hospital, Chongqing, Chongqing, China

Contact Details

Name: Kuansheng Ma, Ph.D

Affiliation: Institute of hepatobiliary surgery,Southwest Hospital

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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