Spots Global Cancer Trial Database for Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma With Major Portal Vein Invasion
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Trial Identification
Brief Title: Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma With Major Portal Vein Invasion
Official Title: Multicenter Phase II Study of Stereotactic Ablative Radiotherapy for Hepatocellular Carcinoma With Major Portal Vein Invasion
Study ID: NCT01850368
Interventions
Study Description
Brief Summary: Recently, several studies reported promising outcomes of patients after external beam radiotherapy (EBRT) for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis. However, conventional EBRT is composed of many fractions (20-35 fractions). On the other hand, stereotactic ablative radiotherapy is a newly emerging treatment method to deliver a high dose of radiation to the target using a few fractions with a high precision within body. SABR increases radiation biologic effect for tumor, makes patients more comfortable due to reduction of the number of hospital visit, and enables patients to receive another treatment more quickly. This study will evaluate SABR effect with 40 Gy in 4 fractions for HCC with major portal vein tumor thrombosis.
Detailed Description:
Eligibility
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Gyeongsang National University Hospital, Jinju, Gyeongsang-nam-do, Korea, Republic of
Dongnam Institute of Radiological & Medical Sciences, Busan, , Korea, Republic of
Keimyung University Dongsan Medical Center, Daegu, , Korea, Republic of
Catholic University Incheon St. Mary's Hospital, Incheon, , Korea, Republic of
Inha University Hospital, Incheon, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, , Korea, Republic of
Soon Chun Hyang University Hospital Seoul, Seoul, , Korea, Republic of
Contact Details
Name: Mi-Sook Kim, MD, PhD
Affiliation: Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences
Role: PRINCIPAL_INVESTIGATOR
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