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Brief Title: Study of Apatinib in Advanced Hepatocellular Carcinoma(HCC)
Official Title: Study of Apatinib in Advanced Hepatocellular Carcinoma(HCC)
Study ID: NCT03046979
Brief Summary: The purpose of this study is to evaluate the efficacy and safety of apatinib in patients with advanced HCC.
Detailed Description: Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver. It is lack of effective drugs for systemic treatment of HCC. Currently, Sorafenib is the only choice approved by FDA for advanced HCC, although it prolongs the survival for less than 3 months. The treatment of advanced HCC still has a long way to go. At present, the relevant phase II and phase III clinical studies of apatinib on advanced HCC are ongoing. Based on our important discovery of our previous clinical studies, we intends to enlarge the sample size and make further observation for the efficacy and safety of apatinib in patients with advanced HCC.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tianjin Medical University Cancer Institute and Hospital, Tianjin, , China
Name: Ti Zhang
Affiliation: Tianjin Medical University Cancer Institute & Hospital
Role: PRINCIPAL_INVESTIGATOR