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Brief Title: Phase II Study of HAIC Using Cisplatin,Leucovorin and 5-Fluorouracil
Official Title: Phase II Study of Hepatic Arterial Infusion Chemotherapy Using Oxaliplatin,Leucovorin and 5-Fluorouracil
Study ID: NCT02987699
Brief Summary: The purpose of this phase II study is to determine the recommended dose, as well as the safety and efficacy of the combination of oxaliplatin, leucovorin and 5-Fu introduced by hepatic arterial infusion chemotherapy (HAIC) in patients with advanced hepatocellular carcinoma (HCC).
Detailed Description: The results of our preliminary pilot study suggested that the combination of oxaliplatin, leucovorin and 5-Fu introduced by hepatic arterial infusion chemotherapy (HAIC) may improve the survivals for advanced stage HCC. Thus, the investigators carried out this prospective randomized control study to determine the recommended dose as well as the safety and efficacy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Cancer Center, Sun Yat-sen University, Guangzhou, Guangdong, China
Name: Ming Shi, Doctor
Affiliation: The Department of Hepatobiliary Pancreatic Oncology of Sun Yat-sen University Cancer Center
Role: PRINCIPAL_INVESTIGATOR