Spots Global Cancer Trial Database for Low Contrast Agent and Radiation Dose Protocol for Liver CT in Patients With HCC

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Trial Identification

Brief Title: Low Contrast Agent and Radiation Dose Protocol for Liver CT in Patients With HCC

Official Title: Low Contrast Agent and Radiation Dose Protocol Liver CT With Deep-learning-based Contrast Boosting Model in Patients at High Risk for HCC: Prospective, Randomized, Single Blinded - Preliminary Study

Study ID: NCT04722120

Conditions

Hepatocellular Carcinoma

Interventions

Low radiation dose CT

Conventional CT (radiation)

Low contrast dose CT

Conventional CT (contrast agent)

Deep-learning based contrast boosting algorithms

Study Description

Brief Summary: The purpose of this study is to investigate the image quality and clinical feasibility of double low-dose liver computed tomography using a deep-learning-based iodine contrast boosting algorithm in participants at high risk for hepatocellular carcinoma.

Detailed Description: The purpose of this study is to investigate the image quality (CNR, subjective inage quality, vessel and lesion conspicuity) and clinical feasibility (rate of lesion detection) of double low-dose liver computed tomography using a deep-learning-based iodine contrast boosting algorithm in participants at high risk for hepatocellular carcinoma.