Spots Global Cancer Trial Database for Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC

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Trial Identification

Brief Title: Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC

Official Title: Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for Patients With Hepatocellular Carcinoma

Study ID: NCT00606385

Conditions

Hepatocellular Carcinoma

Interventions

Liver resection

Study Description

Brief Summary: Short-term outcomes of laparoscopic liver resection is better than those of open liver resection Laparoscopic liver resection is better than open resection in immunological aspects

Detailed Description: Advantages and disadvantages of the laparoscopic compared with the open approach for liver resections 1. Advantages 1) Less postoperative ascites production 2) Reduced postoperative pain 3) Feasible in selected cirrhotics who have contraindications to open surgery 4) Less intra-abdominal adhesions (easier salvage transplantation) 5) Shorter recovery time 6) Shorter length of stay 7) Reduced financial cost 2. Disadvantages 1) No manual palpation or exploration of the liver parenchyma possible (with the pure laparoscopic approach) 2) High demand in surgical skill (especially major resections)