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Brief Title: Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib
Official Title: A Phase 3, Randomized, Double-blind, Controlled Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib
Study ID: NCT01908426
Brief Summary: The purpose of this study is to evaluate the effect of Cabozantinib (XL184) compared with placebo on overall survival in subjects with advanced hepatocellular carcinoma who have received prior sorafenib.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
, Corona, California, United States
, Los Angeles, California, United States
, San Diego, California, United States
, San Francisco, California, United States
, Gainesville, Florida, United States
, Atlanta, Georgia, United States
, Honolulu, Hawaii, United States
, Chicago, Illinois, United States
, Burlington, Massachusetts, United States
, Rochester, Minnesota, United States
, Kansas City, Missouri, United States
, Saint Louis, Missouri, United States
, Las Vegas, Nevada, United States
, East Orange, New Jersey, United States
, New York, New York, United States
, New York, New York, United States
, Valhalla, New York, United States
, Dallas, Texas, United States
, San Antonio, Texas, United States
, Seattle, Washington, United States
, Seattle, Washington, United States
, Spokane, Washington, United States
, Camperdown, New South Wales, Australia
, Concord, New South Wales, Australia
, Darlinghurst, New South Wales, Australia
, Kogarah, New South Wales, Australia
, Westmead, New South Wales, Australia
, Kurralta Park, South Australia, Australia
, Melbourne, Victoria, Australia
, Perth, Western Australia, Australia
, Edegem, Antwerpen, Belgium
, La Louvière, Hainaut, Belgium
, Gent, Oost-Vlaanderen, Belgium
, Liege, , Belgium
, Calgary, Alberta, Canada
, Toronto, Ontario, Canada
, Saskatoon, Saskatchewan, Canada
, Nice, Alpes-Maritimes, France
, Amiens, Somme, France
, Creteil, Val-de-Marne, France
, Besançon, , France
, Bordeaux, , France
, Clermont-Ferrand, , France
, Lille, , France
, Lyon, , France
, Esslingen am Neckar, Baden-Württemberg, Germany
, Tübingen, Baden-Württemberg, Germany
, München, Bayern, Germany
, Frankfurt am Main, Hessen, Germany
, Magdeburg, Sachsen-Anhalt, Germany
, Berlin, , Germany
, Freiburg, , Germany
, Hong Kong, , Hong Kong
, Dublin, , Ireland
, Bologna, Emilia-Romagna, Italy
, Faenza, Emilia-Romagna, Italy
, Meldola, Emilia-Romagna, Italy
, Rimini, Emilia-Romagna, Italy
, Roma, Lazio, Italy
, Roma, Lazio, Italy
, Genova, Liguria, Italy
, Milan, Lombardia, Italy
, Rozzano, Lombardia, Italy
, Palermo, Sicilia, Italy
, Padova, Veneto, Italy
, Goyang, Gyeonggido, Korea, Republic of
, Busan, , Korea, Republic of
, Seongnam, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Seoul, , Korea, Republic of
, Suwon-si, , Korea, Republic of
, Maastricht, Limburg, Netherlands
, Amsterdam, Noord-Holland, Netherlands
, Amsterdam, Noord-Holland, Netherlands
, Leiden, Zuid-Holland, Netherlands
, Auckland, North Island, New Zealand
, Olsztyn, Warminsko-Mazurskie, Poland
, Myslowice, , Poland
, Poznan, , Poland
, Cluj-Napoca, Cluj, Romania
, Brasov, , Romania
, Singapore, , Singapore
, Singapore, , Singapore
, Singapore, , Singapore
, Elche, Alicante, Spain
, Majadahonda, Madrid, Spain
, Torrejon de Ardoz, Madrid, Spain
, Madrid, , Spain
, Madrid, , Spain
, Zaragoza, , Spain
, Liuying Township, Tainan, Taiwan
, Taichung, , Taiwan
, Taipei, , Taiwan
, Edirne, , Turkey
, Gaziantep, , Turkey
, Wirral, England, United Kingdom
, Birmingham, , United Kingdom
, London, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom