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Brief Title: BC3402 in Combination With Durvalumab in Patients With Advanced Hepatocellular Carcinoma
Official Title: A Phase Ib/II Clinical Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BC3402 in Combination With Durvalumab in Patients With Advanced Hepatocellular Carcinoma
Study ID: NCT06111326
Brief Summary: Phase Ib: Dose exploration: To assess the safety, tolerability, and determine the recommended Phase 2 dose (RP2D) of BC3402 in combination with durvalumab in subjects with advanced hepatocellular carcinoma (HCC) Phase II: Dose Expansion: To assess the antitumor activity of BC3402 in combination with durvalumab in subjects with advanced HCC.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Zhongshan Hospital, Fudan University, Shanghai, , China
Name: Jia Fan, MD
Affiliation: Fudan University
Role: PRINCIPAL_INVESTIGATOR