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Brief Title: P1101 and Anti-PD1 for After Curative Surgery of Hepatitis B-related Hepatocellular Carcinoma
Official Title: A Phase I/II Open Label Study to Evaluate Safety and the Prophylactic Effect on Recurrence of Anti-PD1 Monotherapy, P1101 Monotherapy, and Sequential Administration of P1101 and Anti-PD1 After Curative Surgery of HBV-related HCC
Study ID: NCT04233840
Brief Summary: The main purpose of this trial is to evaluate the safety of the new adjuvant treatment of curative HCC, or the treatment of long-acting interferon P1101 alone, or the use of long-acting interferon P1101 and subsequent treatment of anti-PD1, and any efficacy in reducing the recurrence rate of patients after surgery.
Detailed Description: secondary end-point: P1101 and anti-PD1 sequential therapy on hepatitis B (especially on HbsAg).
Minimum Age: 20 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
National Taiwan university Hospital, Taipei city, , Taiwan
Name: Pei-Jer Chen
Affiliation: NTUH
Role: PRINCIPAL_INVESTIGATOR