Spots Global Cancer Trial Database for Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery

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Trial Identification

Brief Title: Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery

Official Title: Opioid Sparing Effect of Thoracic Epidural Analgesia for Open Upper Abdominal Surgery: Prospective Randomized Controlled Trial

Study ID: NCT04920019

Conditions

Hepatoma

Pancreas Cancer

Interventions

Thoracic continuous epidural analgesia

Study Description

Brief Summary: This prospective randomized controlled study is aimed to determine the advantages of thoracic epidural analgesia for open upper abdominal surgery in combination with multimodal analgesia compared with no thoracic epidural analgesia on postoperative pain control. The primary outcome is total opioid consumption in postoperative 72 hours. Secondary outcomes are the success of continuous epidural analgesia or complications of this technique, pain intensity, morbidity and mortality compare to no continuous epidural analgesia.

Detailed Description: Continuous epidural analgesia (CEA) for open upper abdominal surgery has been showed the analgesic analgesia for open abdominal surgery. However the technical difficulty, complications especially hypotension, pruritus of CEA impede the popularity of technique compared to intravenous patient-controlled analgesia (IV PCA) in multimodal analgesia. This study is aimed to study of the role of CEA and multimodal analgesia in open abdominal surgery compare to IV PCA.