Spots Global Cancer Trial Database for Prognosis of Patients With Relapsed/Refractory Hodgkin Lymphoma Treated With IGEV Induction Therapy Before HDCT With AHSCT
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Trial Identification
Brief Title: Prognosis of Patients With Relapsed/Refractory Hodgkin Lymphoma Treated With IGEV Induction Therapy Before HDCT With AHSCT
Official Title: Prognosis of Patients With Relapsed/Refractory Hl Treated With Combination of Ifosfamide, Gemcitabine and Vinorelbine(IGEV) Induction Therapy Before High-dose Chemotherapy (HDCT) With Autologous Hematopoietic Stem Cells Transplantation (AHSCT)
Study ID: NCT01478191
Conditions
Interventions
Study Description
Brief Summary: This is a retrospective analysis of a homogeneous cohort of patients with relapsed/refractory HL that received IGEV scheme as induction therapy to HDCT and AHSCT for reassess the most common prognostic factors and try to identify a prognostic score with clinical and therapeutic relevance by using 6 clinical tools: 1. B symptoms(yes/no) 2. relapse in previously irradiated areas(yes/no) 3. Ann Arbor Stage (III/IV vs I/II) 4. disease status at accrual (refractory vs relapsed) 5. Early relapse within 12 months of Complete Response (CR) versus late relapse after Complete Response (CR) lasting \> l2 months", 6. extranodal involvement (yes/no).
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Ospedale dell'Angelo, Mestre, VE, Italy
A.O.SS. Biagio, Antonio e Cesare Arrigo, Alessandria, , Italy
AORN San G.Moscati, Avellino, , Italy
Centro di riferimento Oncologico - Oncologia Medica A, Aviano (PN), , Italy
Divisione di Ematologia Spedali Civili, Brescia, , Italy
Ospedale di Circolo, Busto Arsizio - VA, , Italy
Divisione di Ematologia Osp.Businco, Cagliari, , Italy
Istituto Oncologico del Mediterraneo, Catania, , Italy
Ospedale civile Divisione di Ematologia, Civitanova Marche (MC), , Italy
Ospedale S Martino, Genova, , Italy
Ospedale San Martino - Divisione di Ematologia, Genova, , Italy
Ospedale Santa Maria Goretti, Latina, , Italy
A O Papardo, Messina, , Italy
Azienda Ospedaliero Universitaria Policlinico Gaetano Martino, Messina, , Italy
Policlinico Maggiore, Milano, , Italy
Ematologia e Trapianto IRCCS, Istituto Nazionale dei Tumori, Milano, , Italy
Osp. San Carlo Borromeo Divisione di Oncologia Medica, Milano, , Italy
Ospedale Niguarda CA' Granda, Milano, , Italy
Policlinico di Modena - Università degli studi, Modena, , Italy
AOU Federico II di Napoli, Napoli, , Italy
Ospedale San Gennaro, Napoli, , Italy
Ospedale Umberto I UO Med. Interna Oncoematologia, Nocera Inferiore (SA), , Italy
SCDU Ematologia, AOU Maggiore della Carità, Novara, , Italy
A.O. di Padova Divisione di Oncologia Medica, Padova, , Italy
Azienda Ospedaliera V. Cervello, Palermo, , Italy
Policlinico P.Giaccone, Palermo, , Italy
Fondazione Policlinico San Matteo, Pavia, , Italy
Ospedale Santo Spirito Dipartimento di Ematologia, Pescara, , Italy
Ospedale Civile G.da Saliceto - UOA Ematologia, Piacenza, , Italy
Azienda Ospedaliera "Bianchi Melacrino Morelli", Reggio Calabria, , Italy
AO Santa Maria Nuova, Reggio Emilia, , Italy
Ospedale Oncologico regionale CROB, Rionero in Vulture (PZ), , Italy
Ospedale S. Eugenio, Roma, , Italy
Policlinico Università Tor Vergata, Roma, , Italy
Univeristà La Sapienza, Roma, , Italy
Clinica Humanitas, Rozzano (MI), , Italy
IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), , Italy
Istituto di Ematologia Università degli studi di Sassari, Sassari, , Italy
Ematologia II OspedaleSan Giovanni Battista Molinette, Torino, , Italy
Presidio Ospedaliero - Unità Complessa Ematologia, Treviso, , Italy
Contact Details
Name: Armando Santoro, Prof.
Affiliation: Istituto Clinico Humanitas
Role: PRINCIPAL_INVESTIGATOR
Name: Monica Balzarotti, Dr.
Affiliation: Istituto Clinico Humanitas
Role: PRINCIPAL_INVESTIGATOR
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