Spots Global Cancer Trial Database for Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers

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Trial Identification

Brief Title: Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers

Official Title: A UK Multicentre Study of Haploidentical Stem Cell Transplantation in Patients With Haematological Malignancies

Study ID: NCT01597219

Conditions

Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

Acute Myeloid Leukaemia

Acute Lymphoblastic Leukaemia

Myelodysplastic Syndrome

Chronic Myeloid Leukaemia

Chronic Lymphocytic Leukaemia

Acquired Bone Marrow Failure Syndromes

Other Haematological Malignancies; Unrelated HSCT Indicated

Interventions

Reduced intensity haplodentical stem cell transplant

Myeloablative haploidentical stem cell transplant

Study Description

Brief Summary: This trial investigates stem cell transplants from partially mismatched donors in patients with blood and bone marrow cancers. The trial will test two kinds of transplants - a full intensity transplant using a high dose of radiotherapy and chemotherapy, and a reduced intensity transplant with lower doses of chemotherapy and radiotherapy. Patients will be entered for the treatment pathway that is most appropriate for their level of health and fitness

Detailed Description: