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Spots Global Cancer Trial Database for Study of the Combination of AFM13 and Pembrolizumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

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Trial Identification

Brief Title: Study of the Combination of AFM13 and Pembrolizumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Official Title: A Phase 1b Dose Escalation Study to Assess the Safety of AFM13 in Combination With Pembrolizumab in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma (KEYNOTE- 206)

Study ID: NCT02665650

Interventions

AFM13
Pembrolizumab

Study Description

Brief Summary: The purpose of this study is to establish a dosing regimen for the combination therapy of AFM13 and pembrolizumab (MK-3475) in patients with relapsed or refractory (R/R) Hodgkin Lymphoma (HL) and to assess the safety and tolerability of this combination therapy.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of Alabama Comprehensive Cancer Center, Birmingham, Alabama, United States

Mayo Clinic, Scottsdale, Arizona, United States

City of Hope National Medical Center, Duarte, California, United States

Ronald Reagan UCLA Medical Center, Los Angeles, California, United States

Yale Cancer Center, New Haven, Connecticut, United States

University of Miami Sylvester Comprehensive Cancer Center, Coral Gables, Florida, United States

Mayo Clinic, Jacksonville, Florida, United States

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

Dana-Farber Cancer Institute, Boston, Massachusetts, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

Mayo Clinic, Rochester, Minnesota, United States

Washington University Medical Center, Saint Louis, Missouri, United States

Providence Portland Medical Center, Providence Cancer Center, Portland, Oregon, United States

University of Texas Southwestern Medical Center, Dallas, Texas, United States

Institut Catala d'Oncologia (ICO) L'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain

Fundacion Privada Instituto de Investigacion Oncologica de Vall Hebron, Barcelona, , Spain

Hospital Universitario 12 de Octubre, Servicio de Hematologia, Madrid, , Spain

Salamanca University Hospital, Salamanca, , Spain

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

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