Spots Global Cancer Trial Database for Wearable Sensors and Molecular Omics to Detect and Mitigate Cell Therapy Adverse Events
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Trial Identification
Brief Title: Wearable Sensors and Molecular Omics to Detect and Mitigate Cell Therapy Adverse Events
Official Title: Wearable Sensors and Molecular Omics to Detect and Mitigate Cell Therapy Adverse Events
Study ID: NCT05123001
Interventions
Study Description
Brief Summary: The purpose of this study is to monitor physiological and molecular changes during and following CAR-T cancer cell therapy, towards improved management of adverse events including Cytokine Release Syndrome and neurotoxicity. Our study aims are to improved early detection and precise management of adverse events for patients receiving Chimeric antigen receptor T- cell (CAR-T): 1. To assess the feasibility, including accuracy, usability, and usefulness of wearable sensors in CAR-T patients. 2. To generate comprehensive multiomic profile analysis following CAR-T therapy. 3. To perform integrated analysis of wearables sensor data, omics data, and symptom/clinical data.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Stanford University, Palo Alto, California, United States
Contact Details
Name: Surbhi Sidana
Affiliation: Stanford University
Role: PRINCIPAL_INVESTIGATOR
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