Spots Global Cancer Trial Database for A Frontline Therapy Trial in Participants With Advanced Classical Hodgkin Lymphoma
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Trial Identification
Brief Title: A Frontline Therapy Trial in Participants With Advanced Classical Hodgkin Lymphoma
Official Title: A Randomized, Open-label, Phase 3 Trial of A+AVD Versus ABVD as Frontline Therapy in Patients With Advanced Classical Hodgkin Lymphoma
Study ID: NCT01712490
Conditions
Study Description
Brief Summary: This open-label, randomized, 2-arm, multicenter, phase 3 study has the primary objective of comparing the modified progression-free survival (mPFS) obtained with brentuximab vedotin (ADCETRIS®) plus AVD (doxorubicin \[Adriamycin\], vinblastine, and dacarbazine; abbreviated A+AVD) versus that obtained with ABVD (doxorubicin \[Adriamycin\],bleomycin, vinblastine, and dacarbazine) for the frontline treatment of advanced classical Hodgkin lymphoma(HL)
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
, Birmingham, Alabama, United States
, Gilbert, Arizona, United States
, Tucson, Arizona, United States
, Burbank, California, United States
, Duarte, California, United States
, Fresno, California, United States
, Fullerton, California, United States
, La Jolla, California, United States
, Long Beach, California, United States
, Los Angeles, California, United States
, Sacramento, California, United States
, San Luis Obispo, California, United States
, Santa Barbara, California, United States
, Santa Monica, California, United States
, Stanford, California, United States
, Colorado Springs, Colorado, United States
, Denver, Colorado, United States
, Lonetree, Colorado, United States
, Washington, District of Columbia, United States
, Fort Myers, Florida, United States
, Jacksonville, Florida, United States
, Miami, Florida, United States
, Orlando, Florida, United States
, Lawrenceville, Georgia, United States
, Chicago, Illinois, United States
, Maywood, Illinois, United States
, Niles, Illinois, United States
, Zion, Illinois, United States
, Fort Wayne, Indiana, United States
, Goshen, Indiana, United States
, Indianapolis, Indiana, United States
, Iowa City, Iowa, United States
, Fairway, Kansas, United States
, Baltimore, Maryland, United States
, Bethesda, Maryland, United States
, Boston, Massachusetts, United States
, Ann Arbor, Michigan, United States
, Detroit, Michigan, United States
, Minneapolis, Minnesota, United States
, Rochester, Minnesota, United States
, Saint Louis, Missouri, United States
, Springfield, Missouri, United States
, Lincoln, Nebraska, United States
, Omaha, Nebraska, United States
, Las Vegas, Nevada, United States
, Basking Ridge, New Jersey, United States
, Hackensack, New Jersey, United States
, Morristown, New Jersey, United States
, Albuquerque, New Mexico, United States
, Albany, New York, United States
, Bronx, New York, United States
, Commack, New York, United States
, New York, New York, United States
, Rochester, New York, United States
, Rockville Centre, New York, United States
, Charlotte, North Carolina, United States
, Raleigh, North Carolina, United States
, Bismarck, North Dakota, United States
, Cincinnati, Ohio, United States
, Columbus, Ohio, United States
, Oklahoma City, Oklahoma, United States
, Eugene, Oregon, United States
, Hershey, Pennsylvania, United States
, Philadelphia, Pennsylvania, United States
, Charleston, South Carolina, United States
, Greenville, South Carolina, United States
, Chattanooga, Tennessee, United States
, Knoxville, Tennessee, United States
, Nashville, Tennessee, United States
, Austin, Texas, United States
, Dallas, Texas, United States
, Houston, Texas, United States
, San Antonio, Texas, United States
, Tyler, Texas, United States
, Salt Lake City, Utah, United States
, Fairfax, Virginia, United States
, Richmond, Virginia, United States
, Kennewick, Washington, United States
, Seattle, Washington, United States
, Vancouver, Washington, United States
, Yakima, Washington, United States
, Morgantown, West Virginia, United States
, Milwaukee, Wisconsin, United States
, Kingswood, New South Wales, Australia
, St Leonards, New South Wales, Australia
, Westmead, New South Wales, Australia
, South Brisbane, Queensland, Australia
, Bedford Park, South Australia, Australia
, Hobart, Tasmania, Australia
, East Melbourne, Victoria, Australia
, Geelong, Victoria, Australia
, Heidelberg, Victoria, Australia
, Parkville, Victoria, Australia
, Perth, Western Australia, Australia
, Antwerpen, , Belgium
, Brugge, , Belgium
, Gent, , Belgium
, Salvador, Bahia, Brazil
, Curitiba, Parana, Brazil
, Porto Alegre, Rio Grande Do Sul, Brazil
, Santo Andre, Sao Paulo, Brazil
, Rio De Janeiro, , Brazil
, Sao paulo, , Brazil
, Edmonton, Alberta, Canada
, Vancouver, British Columbia, Canada
, Winnipeg, Manitoba, Canada
, Halifax, Nova Scotia, Canada
, Toronto, Ontario, Canada
, Montreal, Quebec, Canada
, Saskatoon, Saskatchewan, Canada
, Hradec Kralove, , Czechia
, Prague, , Czechia
, Praha 10, , Czechia
, Aalborg, , Denmark
, Aarhus C, , Denmark
, Copenhagen, , Denmark
, Odense C, , Denmark
, Roskilde, , Denmark
, Argenteuil, Cedex, France
, La Tronche, , France
, Limoges, , France
, Paris, , France
, Lai Chi Kok, Kowloon, Hong Kong
, Hong Kong, , Hong Kong
, Tuen Mun, , Hong Kong
, Budapest, , Hungary
, Debrecen, , Hungary
, Gyor, , Hungary
, Pecs, , Hungary
, Szeged, , Hungary
, Modena, Emilia-Romagna, Italy
, Roma, Lazio, Italy
, Alessandria, , Italy
, Bologna, , Italy
, Cagliari, , Italy
, Cuneo, , Italy
, Genova, , Italy
, Milano, , Italy
, Napoli, , Italy
, Rionero In Volture, , Italy
, Rome, , Italy
, Rozzano, , Italy
, Torrette Di Ancona, , Italy
, Minami-ku, Fukuoka-city, Japan
, Higashi-ku, Fukuoka, Japan
, Minami-ku, Hiroshima-city, Japan
, Showamachi, Maebashi-city, Japan
, Chikusa-ku, Nagoya, Japan
, Suita, Osaka Prefecture, Japan
, Aoba-ku, Sendai-city, Japan
, Chuo-ku, , Japan
, Isehara-shi, , Japan
, Koto-ku, , Japan
, Goyang, Gyeonggi, Korea, Republic of
, Hwasun-gun, Jeollanam-do, Korea, Republic of
, Seocho-gu, Seoul, Korea, Republic of
, Busan, , Korea, Republic of
, Daegu, , Korea, Republic of
, Incheon, , Korea, Republic of
, Jeonju, , Korea, Republic of
, Seoul, , Korea, Republic of
, Bergen, , Norway
, Oslo, , Norway
, Gdansk, , Poland
, Katowice, , Poland
, Krakow, , Poland
, L0dz, , Poland
, Olsztyn, , Poland
, Warszawa, , Poland
, Wroclaw, , Poland
, Saint-Petersburg, Poselok Pesochny, Russian Federation
, Ufa, Republic Of Bashkortostan, Russian Federation
, Kazan, Republic Tatrstan, Russian Federation
, Moscow, , Russian Federation
, Moskva, , Russian Federation
, St.Petersburg, , Russian Federation
, Johannesburg, Gauteng, South Africa
, Pretoria, Gauteng, South Africa
, Amanzimtoti, Kwa Zulu Natal, South Africa
, Bloemfontein, , South Africa
, Cape Town, , South Africa
, Badalona, , Spain
, Barcelona, , Spain
, Marbella, , Spain
, Pamplona, , Spain
, Salamanca, , Spain
, Santiago de Compostela, , Spain
, Valencia, , Spain
, Changhua City, , Taiwan
, Chiayi County 613, , Taiwan
, Tainan, , Taiwan
, Taipei, , Taiwan
, Taoyuan County, , Taiwan
, Ankara, , Turkey
, Istanbul, , Turkey
, Samsun, , Turkey
, Truro, Cornwall, United Kingdom
, Aberdeen, Scotland, United Kingdom
, Glasgow, Scotland, United Kingdom
, Sutton, Surrey, United Kingdom
, Cardiff, Wales, United Kingdom
, Birmingham, , United Kingdom
, Canterbury, , United Kingdom
, Exeter, , United Kingdom
, Inverness, , United Kingdom
, Leicester, , United Kingdom
, Lincoln, , United Kingdom
, Liverpool, , United Kingdom
, London, , United Kingdom
, Manchester, , United Kingdom
, Norfolk, , United Kingdom
, Northwood, , United Kingdom
, Nottingham, , United Kingdom
, Oxford, , United Kingdom
, Romford, , United Kingdom
, Southampton, , United Kingdom
Contact Details
Name: Study Director
Affiliation: Takeda
Role: STUDY_DIRECTOR
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