Spots Global Cancer Trial Database for Safety and Efficacy Trial of a RNActive®-Derived Prostate Cancer Vaccine in Hormone Refractory Disease
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Trial Identification
Brief Title: Safety and Efficacy Trial of a RNActive®-Derived Prostate Cancer Vaccine in Hormone Refractory Disease
Official Title: Safety and Efficacy Trial of a RNActive®-Derived Prostate Cancer Vaccine in Hormone Refractory Disease
Study ID: NCT00831467
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to determine the efficacy and safety of a new vaccine in hormone refractory prostate cancer
Detailed Description: Immunotherapy of prostate cancer is a promising approach for the treatment of advanced or recurrent forms of prostate cancer. Recently, immunotherapy of prostate cancer has been facilitated by the identification of a number of prostate specific antigens that are expressed in healthy and tumor prostate tissues. For prostatectomized patients, such antigens offer ideal targets for immunotherapy as they are only present in tumor but not in healthy tissue. The use of prostate specific antigens in a cancer vaccine is one attractive option for cancer immunotherapy.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
Universitätsklinikum Aachen, Urologische Klinik, Aachen, , Germany
Charité Universitätsmedizin Berlin, Urologische Klinik u. Hochschulambulanz, Berlin, , Germany
Universitätsklinikum Carl Gustav Carus der TU Dresden, Klinik und Poliklinik für Urologie, Dresden, , Germany
Universitätsklinikum Essen, Klinik und Poliklinik für Urologie, Uroonkologie und Kinderurologie, Essen, , Germany
Klinikum der JWG-Universität, Klinik für Urologie und Kinderurologie, Frankfurt am Main, , Germany
Universitätsklinikum Freiburg, Abteilung Urologie, Freiburg, , Germany
UKSH Campus Lübeck, Klinik und Poliklinik fur Urologie, Lübeck, , Germany
Johannes-Gutenberg-Universität Mainz, Urologische Klinik und Poliklinik, Mainz, , Germany
Universitätsmedizin Mannheim, Urologische Klinik, Mannheim, , Germany
Klinikum rechts der Isar der TU München, Urologische Klinik und Poliklinik, München, , Germany
Klinik für Urologie, Universitätsklinikum Tübingen, Tübingen, , Germany
Fondazione scientifica Istituto San Raffaele, Milano, , Italy
Contact Details
Name: Kurt Miller, Professor
Affiliation: PMID: 19143027
Role: PRINCIPAL_INVESTIGATOR
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