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Brief Title: A Global Study to Compare the Effects of Fulvestrant and Arimidex in a Subset of Patients With Breast Cancer.
Official Title: A Randomised, Double-blind, Parallel-group, Multicentre, Phase III Study to Compare the Efficacy and Tolerability of Fulvestrant (FASLODEX) 500 mg With Anastrozole (ARIMIDEX) 1 mg as Hormonal Treatment for Postmenopausal Women With Hormone Receptor-Positive Locally Advanced or Metastatic Breast Cancer Who Have Not Previously Been Treated With Any Hormonal Therapy.
Study ID: NCT01602380
Brief Summary: The purpose of the study is to compare how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast cancer who have not had prior hormonal treatment.
Detailed Description: A Randomised, Double-blind, Parallel-group, Multicentre, Phase III Study to Compare the Efficacy and Tolerability of Fulvestrant (FASLODEX) 500 mg with Anastrozole (ARIMIDEX) 1 mg as Hormonal Treatment for Postmenopausal Women with Hormone Receptor-Positive Locally Advanced or Metastatic Breast Cancer Who Have Not Previously Been Treated With Any Hormonal Therapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Research Site, Modesto, California, United States
Research Site, Savannah, Georgia, United States
Research Site, Auburn, Maine, United States
Research Site, Worcester, Massachusetts, United States
Research Site, Detroit, Michigan, United States
Research Site, Saint Louis, Missouri, United States
Research Site, Lincoln, Nebraska, United States
Research Site, Somerset, New Jersey, United States
Research Site, Columbus, Ohio, United States
Research Site, Montgomery, Ohio, United States
Research Site, Memphis, Tennessee, United States
Research Site, Salt Lake City, Utah, United States
Research Site, La Rioja, , Argentina
Research Site, Mar del Plata, , Argentina
Research Site, Pergamino, , Argentina
Research Site, Rosario, , Argentina
Research Site, Porto Alegre, , Brazil
Research Site, Santo Andre, , Brazil
Research Site, Abbotsford, British Columbia, Canada
Research Site, Vancouver, British Columbia, Canada
Research Site, Kitchener, Ontario, Canada
Research Site, Thunder Bay, Ontario, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Montreal, Quebec, Canada
Research Site, Chengdu, , China
Research Site, Dalian, , China
Research Site, Fuzhou, , China
Research Site, Guangzhou, , China
Research Site, Shanghai, , China
Research Site, Shenyang, , China
Research Site, Suzhou, , China
Research Site, Tianjin, , China
Research Site, Praha 5, , Czechia
Research Site, Pribram, , Czechia
Research Site, Avellino, , Italy
Research Site, Bari, , Italy
Research Site, Benevento, , Italy
Research Site, Catania, , Italy
Research Site, Genova, , Italy
Research Site, Pisa, , Italy
Research Site, Roma, , Italy
Research Site, Roma, , Italy
Research Site, Roma, , Italy
Research Site, Treviglio, , Italy
Research Site, Fukuoka-shi, , Japan
Research Site, Hamamatsu-shi, , Japan
Research Site, Kagoshima-shi, , Japan
Research Site, Kumamoto-shi, , Japan
Research Site, Matsuyama-shi, , Japan
Research Site, Mitaka-shi, , Japan
Research Site, Nishinomiya-shi, , Japan
Research Site, Osaka-city, , Japan
Research Site, Sakai-shi, , Japan
Research Site, Suita-shi, , Japan
Research Site, Merida, , Mexico
Research Site, Mexico, D.F., , Mexico
Research Site, Monterrey, , Mexico
Research Site, Monterrey, , Mexico
Research Site, Monterrey, , Mexico
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Lima, , Peru
Research Site, Katowice, , Poland
Research Site, Lublin, , Poland
Research Site, Łódź, , Poland
Research Site, Braila, , Romania
Research Site, Craiova, , Romania
Research Site, Onesti, , Romania
Research Site, Timisoara, , Romania
Research Site, Barnaul, , Russian Federation
Research Site, Moscow, , Russian Federation
Research Site, Omsk, , Russian Federation
Research Site, Ryazan, , Russian Federation
Research Site, Saint Petersburg, , Russian Federation
Research Site, Saint Petersburg, , Russian Federation
Research Site, St-Petersburg, , Russian Federation
Research Site, St. Petersburg, , Russian Federation
Research Site, St.Petersburg, , Russian Federation
Research Site, Tomsk, , Russian Federation
Research Site, Bardejov, , Slovakia
Research Site, Bratislava, , Slovakia
Research Site, Bratislava, , Slovakia
Research Site, Trencin, , Slovakia
Research Site, Cape Town, , South Africa
Research Site, Cape town, , South Africa
Research Site, Cape Town, , South Africa
Research Site, Pietermaritzburg, , South Africa
Research Site, Pretoria, , South Africa
Research Site, Pretoria, , South Africa
Research Site, Madrid, , Spain
Research Site, Madrid, , Spain
Research Site, Pamplona, , Spain
Research Site, Pozuelo de Alarcon, , Spain
Research Site, Sabadell, , Spain
Research Site, Sevilla, , Spain
Research Site, Sevilla, , Spain
Research Site, Sevilla, , Spain
Research Site, Valencia, , Spain
Research Site, Valencia, , Spain
Research Site, Taichung, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Taipei, , Taiwan
Research Site, Ankara, , Turkey
Research Site, Gaziantep, , Turkey
Research Site, Cherkasy, , Ukraine
Research Site, Dnipro, , Ukraine
Research Site, Donetsk, , Ukraine
Research Site, Ivano-Frankivsk, , Ukraine
Research Site, Kharkiv Region, , Ukraine
Research Site, Kyiv, , Ukraine
Research Site, Lviv, , Ukraine
Research Site, Mariupol, , Ukraine
Research Site, Uzhhorod, , Ukraine
Research Site, Vinnytsia, , Ukraine
Research Site, Airdrie, , United Kingdom
Research Site, Derby, , United Kingdom
Research Site, Stoke-on-Trent, , United Kingdom
Name: Shankar S, MD
Affiliation: AstraZeneca
Role: STUDY_DIRECTOR
Name: John Robertson, MD
Affiliation: Graduate Medicine and Health School, University of Nottingham, UK
Role: PRINCIPAL_INVESTIGATOR
Name: Matthew Ellis, DM
Affiliation: Washington University School of Medicine, USA
Role: PRINCIPAL_INVESTIGATOR