Spots Global Cancer Trial Database for Post-treatment Surveillance in HPV+ Oropharyngeal SCC

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Trial Identification

Brief Title: Post-treatment Surveillance in HPV+ Oropharyngeal SCC

Official Title: Circulating HPV DNA for Post-treatment Surveillance in HPV-positive Oropharyngeal Squamous Cell Carcinoma

Study ID: NCT04965792

Conditions

HPV

Oropharyngeal Squamous Cell Carcinoma

Interventions

Screening

Study Description

Brief Summary: In this research study the investigators are examining a blood test to detect HPV DNA in the blood that can possibly detect cancer recurrence earlier than with standard surveillance measures.

Detailed Description: This research study involves blood tests to detect HPV DNA at regular time points after treatment for HPV-positive oropharyngeal squamous cell carcinoma (HPV-OPC). Participants may undergo scans based on the results of the blood tests. Study participants will also be asked to complete quality of life questionnaires periodically. Participation in this study may last for up to 5 years. It is expected that about 150 people will take part in this research study.