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Spots Global Cancer Trial Database for Acceptability of Human Papillomavirus (HPV) Vaccine in Female Sex Workers

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Trial Identification

Brief Title: Acceptability of Human Papillomavirus (HPV) Vaccine in Female Sex Workers

Official Title: Acceptability and Feasibility of a Modified HPV Vaccine Schedule in Brothel Based Female Sex Workers in Peru

Study ID: NCT00925288

Interventions

Gardasil

Study Description

Brief Summary: The primary objectives of this study are to determine the acceptance and potential for the effective use of HPV vaccine in the standard and a modified schedule in female sex workers. Secondary objectives include ascertaining the prevalence of HPV types among female sex workers by age and sexual experience.

Detailed Description: FSWs are at higher risk of HPV infection and presumably cervical cancer, and the recently available vaccine has been shown to protect against persistent infection from these types. If this study gives evidence showing the vaccine is acceptable in preventing cervical HPV infection by types 16 and 18 in this population, then the burden of cervical cancer and cancer precursors could be drastically decreased through widespread vaccination of this target group. Vaccination at the point of entry of brothel based sex work may become a requirement to lower the burden of cervical cancer among FSWs and also among all other sex partners of clients of FSWs. A modified schedule may prove beneficial for FSWs in Peru to complete the vaccine regimen.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT

Sex: FEMALE

Healthy Volunteers: Yes

Locations

NGO Via Libre, Lima, , Peru

Contact Details

Name: Neal Halsey, MD

Affiliation: Johns Hopkins Bloomberg School of Public Health

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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