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Brief Title: Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
Official Title: Effect of Short Term Adrenal Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess (CBS003)
Study ID: NCT01422707
Brief Summary: Short term hydrocortisone to test whether improves excess androgen production from adrenal gland and ovaries
Detailed Description: This study will test whether short-term suppression of adrenal function can ameliorate androgen (male hormone) overproduction in overweight girls with androgen excess. The investigators hypothesize that one month of oral hydrocortisone administration will improve androgen levels in girls with adrenal androgen overproduction. Specifically, this intervention will improve androgen levels after adrenal stimulation testing with adrenocorticotropin hormone (ACTH).
Minimum Age: 7 Years
Eligible Ages: CHILD, ADULT
Sex: FEMALE
Healthy Volunteers: No
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States
Name: Christine M. Burt Solorzano, MD
Affiliation: University of Virginia
Role: PRINCIPAL_INVESTIGATOR