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Brief Title: Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess
Official Title: Effect of Short Term Ovarian Suppression on Androgen Overproduction in Overweight Girls With Androgen Excess (CBS007)
Study ID: NCT01422096
Brief Summary: This study will test whether short-term suppression of ovarian function can ameliorate androgen (male hormone) overproduction in overweight girls with androgen excess. The investigators hypothesize that one dose of depot leuprolide agonist administration will improve androgen levels in girls with ovarian androgen overproduction. Specifically, this intervention will improve androgen levels after ovarian stimulation testing with recombinant human chorionic gonadotropin (rhCG).
Detailed Description:
Minimum Age: 7 Years
Eligible Ages: CHILD, ADULT
Sex: FEMALE
Healthy Volunteers: No
University of Virginia Center for Research in Reproduction, Charlottesville, Virginia, United States
Name: Christine M. Burt Solorzano, MD
Affiliation: University of Virginia
Role: PRINCIPAL_INVESTIGATOR