Spots Global Cancer Trial Database for Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions

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Trial Identification

Brief Title: Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions

Official Title: Clinical Assessment of the Treatment With Diazoxide in Children Suffering From Obesity and Hyperinsulinemia Secondary to Surgery of Hypothalamic-pituitary Lesions

Study ID: NCT00306683

Conditions

Hypothalamic-pituitary Lesions

Craniopharyngiomas

Interventions

DIAZOXIDE

Study Description

Brief Summary: In children treated for intracranial lesions, the 2 factors of the obesity are : the location of the lesion (hypothalamic-pituitary region) and craniopharyngiomas

Detailed Description: Approximately 80 % of the hypothalamic-pituitary lesions that occur in children are craniopharyngiomas with one or three cases per 1 million children each year. One major problem remains unsolved : the obesity This study is performed to optimize the management of the children with hypothalamic-pituitary lesions by reducing the hyperinsulinemia due to the lesion and the surgery