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Brief Title: MRI-based Synthetic CT Images of the Head and Neck
Official Title: Artificial Intelligence Driven Synthetic CT to Substitute CT Scans of the Head and Neck Region
Study ID: NCT06016335
Brief Summary: In case of surgical procedures in the head and neck region, MRI in combination with CT of the bone is often the standard modality to visualise bony landmarks for planning, navigation and risk assessment. An important downside of a CT scan is the associated radiation exposure, especially in children. An additional downside is the sedation or general anaesthesia needed for both the MRI and CT scan session in very young children. These downsides could be removed if the CT scan can be substituted by an MRI sequence that can provide the same information as CT. This project aims to determine the feasibility of recreating CT like images of the craniofacial bones from MRI images using machine learning techniques.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Amsterdam University Medical Center, Amsterdam, , Netherlands
Name: Paul Merkus, MD PhD
Affiliation: Amsterdam UMC, location VUmc
Role: PRINCIPAL_INVESTIGATOR