Spots Global Cancer Trial Database for Clinico-immunological Characterization and Immune Tolerance Breakdown in HU-autoimmunity
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Trial Identification
Brief Title: Clinico-immunological Characterization and Immune Tolerance Breakdown in HU-autoimmunity
Official Title: Clinico-immunological Characterization and Immune Tolerance Breakdown in HU-autoimmunity
Study ID: NCT05745792
Conditions
Study Description
Brief Summary: Phenotypic characterization of patients with Hu-Abs, including the different neurological presentation and the presence or not of an underlying cancer. Analysis and clinical correlation of the diagnostic techniques for Hu-Abs detection (immunofluorescence, immunodot/Western blot, and CBA) in serum and/or CSF. Genomic and transcriptomic features of tumors (histological and immune infiltrate characteristics, transcriptomic profile, mutational status).
Detailed Description:
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Centre de référence des syndromes neurologiques paranéoplasiques et encéphalites autoimmunes, Lyon, , France
Contact Details
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