Spots Global Cancer Trial Database for Prospective Comparison of Immunological Benefit of Laparoscopic Colectomy

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Trial Identification

Brief Title: Prospective Comparison of Immunological Benefit of Laparoscopic Colectomy

Official Title: Prospective Comparative Study of Immunological Benefit Between Laparoscopic Colectomy and Open Colectomy

Study ID: NCT00744159

Conditions

Immunity

Interventions

Study Description

Brief Summary: This study aimed to clarify existence of immunological benefit of laparoscopic colon cancer surgery compared to open colon surgery.

Detailed Description: Patients with clinical stage Ⅲ left colon and upper rectal cancer were prospectively assigned to undergo LC (n=35) or OC (n=39). Factors related to cellular immunity of host (total lymphocyte count, CD4 lymphocyte, CD8 lymphocyte, CD4/CD8 ratio, HLA-DR expression on monocyte (mHLA-DR)) were examined preoperatively, on the 1st day of operation (POD1) and the 5th day of operation (POD5).