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Brief Title: Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
Official Title: Chemotherapy-induced Cognitive and Brain Changes in Older Adults With Breast Cancer
Study ID: NCT02290834
Brief Summary: This research study evaluates the effect of chemotherapy on cognition (thinking) and the brain in people with breast cancer.
Detailed Description: * This study is being done to study effects of chemotherapy (cancer treatment) on the brain and cognition (thinking). "Chemo-brain" is a term sometimes used to refer to effects of chemotherapy on the brain and cognition (thinking). * This study is being done to test for "chemo-brain" in older adults with breast cancer treated with chemotherapy, and to identify people who are most likely to be affected. The investigators will look at thinking abilities and brain images before and after chemotherapy to see if it can help identify people at risk for cognitive side effects of the treatment, and to better understand effects of treatment on brain structure and function. * The investigators are looking for participants who have either been recently recently diagnosed breast cancer participant or a healthy volunteer. * What is involved in the study: * Memory and Thinking Tests * Imaging: Either MRI/or MRI and PET Scans
Minimum Age: 60 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: Yes
Massachusetts General Hospital, Boston, Massachusetts, United States
Massachusetts General Hospital/North Shore Cancer Center, Salem, Massachusetts, United States
Name: Michael Parsons, PhD
Affiliation: Massachusetts General Hospital
Role: PRINCIPAL_INVESTIGATOR