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Brief Title: Digestive Biobank for Exploring Microbiota-host Interactions
Official Title: Digestive Biobank for Exploring Microbiota-host Interactions
Study ID: NCT05704413
Brief Summary: Constitution of a biobank of tissues, whole blood and plasma samples and stools to identify markers associated with treatment response, postoperative morbidity including neuro-cognitive and mood complications and prognosis of Inflammatory Bowel disease or colorectal cancer.
Detailed Description: Inflammatory Bowel disease (Crohn, Ulcerative colitis) and colorectal cancer are frequent affections and the microbiota plays a major role in their physiopathology involving the immune system. In this setting, the interplay between gut microbiota and brain is still unexplored. To evaluate the interaction of the microbiota and the immune system with the host in these two chronic diseases, we aim to create a prospective biobank. A small amount of tissue will be taken during surgery. A whole blood, plasma and stoll samples will also be taken from the patient. All samples will be anonymized.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Service de Chirurgie Viscérale - Hôpital Saint Antoine, Paris, , France
Name: Jérémie LEFEVRE, PU-PH
Affiliation: Assistance Publique - Hôpitaux de Paris
Role: PRINCIPAL_INVESTIGATOR