Spots Global Cancer Trial Database for Digestive Biobank for Exploring Microbiota-host Interactions

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Trial Identification

Brief Title: Digestive Biobank for Exploring Microbiota-host Interactions

Official Title: Digestive Biobank for Exploring Microbiota-host Interactions

Study ID: NCT05704413

Conditions

Inflammatory Bowel Diseases

Crohn Disease

Ulcerative Colitis

Colorectal Cancer

Indeterminate Colitis

Interventions

Study Description

Brief Summary: Constitution of a biobank of tissues, whole blood and plasma samples and stools to identify markers associated with treatment response, postoperative morbidity including neuro-cognitive and mood complications and prognosis of Inflammatory Bowel disease or colorectal cancer.

Detailed Description: Inflammatory Bowel disease (Crohn, Ulcerative colitis) and colorectal cancer are frequent affections and the microbiota plays a major role in their physiopathology involving the immune system. In this setting, the interplay between gut microbiota and brain is still unexplored. To evaluate the interaction of the microbiota and the immune system with the host in these two chronic diseases, we aim to create a prospective biobank. A small amount of tissue will be taken during surgery. A whole blood, plasma and stoll samples will also be taken from the patient. All samples will be anonymized.