Spots Global Cancer Trial Database for Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE)
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Trial Identification
Brief Title: Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or Tufting Enteropathy (TE)
Official Title: Characterization Phenotypic and Genetic Study of the Intestinal Epithelial Dysplasia or TE
Study ID: NCT01114035
Study Description
Brief Summary: This PHRC is centred on the intestinal epithelial dysplasia ( DEI) or " tufting enteropathy " or TE the clinical and histo-pathological descriptions of which are specified well to the digestive plan(shot).
Detailed Description: The objectives of this PHRC are: * the phenotypic analysis of the intestinal epithelial dysplasia by clinical and histo-pathological investigations. * the identification of proteins involved at the intestinal level in the differentiation, the proliferation and the membership of the epithelial cells * from the phenotypic study, a genetic analysis of type maps by homozygote on the whole genome partner in an approach guided by possible candidate genes * the study of the genes, chosen according to their location, to their profile of expression, and to their function in touch with the pathogenic hypotheses
Eligibility
Minimum Age:
Eligible Ages: CHILD
Sex: ALL
Healthy Volunteers: No
Locations
Necker Hospital, Paris, , France
Contact Details
Name: Olivier Goulet, MD, PhD
Affiliation: Assistance Publique - Hôpitaux de Paris
Role: PRINCIPAL_INVESTIGATOR
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