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Brief Title: A Study of Propranolol to Treat Kaposi Sarcoma
Official Title: A Phase II Study of Propranolol for the Treatment of Kaposi Sarcoma in Children and Adults
Study ID: NCT05797662
Brief Summary: A clinical study of propranolol for the treatment of Kaposi Sarcoma in children and adults. This study will be an open-label single armed treatment trial that will test the effectiveness and the safety of treating Kaposi Sarcoma with propranolol.
Detailed Description: Eligible study participants will receive propanolol twice daily for an initial 12-week period. At the conclusion of 12-weeks, response will be assessed. Participants who achieve a complete or partial response will continue propanolol for an additional 6 weeks or 12 weeks, respectively.
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Fundación Huésped, Buenos Aires, , Argentina
Instituto Nacional de Câncer José de Alencar, Rio De Janeiro, , Brazil
Complexo Hospitalar Universitário Professor Edgard Santos, Salvador, , Brazil
Moi University School of Medicine, Eldoret, , Kenya
UNC Project Malawi, Lilongwe, , Malawi
Instituto Nacional de Cancerologia, Ciudad de Mexico, , Mexico
African Cancer Institute at Stellenbosch, Cape Town, , South Africa
Uganda Cancer Institute, Kampala, , Uganda
University of Zimbabwe College of Health Sciences, Harare, , Zimbabwe
Name: Shane McAllister, Md, PhD
Affiliation: University of Minnesota Medical School Department of Pediatrics
Role: STUDY_CHAIR