Spots Global Cancer Trial Database for Ketamine and Postoperative Depressive Symptom-PASSION
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Trial Identification
Brief Title: Ketamine and Postoperative Depressive Symptom-PASSION
Official Title: Effect of Low-dose Ketamine on Postoperative Depressive Symptom in Patients Undergoing Intracranial Tumor Resection (PASSION)
Study ID: NCT03086148
Study Description
Brief Summary: Perioperative depression symptom (PDS) is one of the common mental comorbidity, and influences the clinical outcomes and prognosis. However, there is no rapid acting treatment to deal with it during the limited hospital stay. This study aims to determine whether ketamine could improve the depressive symptom of peirioperative patients. It will also examine the safety for administrating ketamine as an antidepressant intraoperatively. Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium. This trial also will bring great concerns on patients with perioperative mental health and explore the measures to improve their psycho-related prognosis.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Beijing TianTan Hospital, Beijing, , China
Contact Details
Name: Ruquan Han, M.D., Ph.D
Affiliation: Department of Anesthesiology, Beijing Tiantan Hospital
Role: STUDY_CHAIR
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