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Brief Title: Quality of Life of Adult Cancer Survivors Who Have Undergone a Previous Bone Marrow or Peripheral Stem Cell Transplant for a Childhood Hematologic Cancer
Official Title: The Quality of Life of Adult Survivors Who Received a Marrow Transplant as a Child
Study ID: NCT00126477
Brief Summary: RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of hematologic cancer and may help improve the quality of life for future cancer survivors. PURPOSE: This clinical trial is studying the quality of life of adult cancer survivors who have undergone a previous bone marrow or peripheral stem cell transplant for a childhood hematologic cancer.
Detailed Description: OBJECTIVES: * Determine the extent to which adult cancer survivors who have undergone prior bone marrow or peripheral blood stem cell transplantation for a pediatric hematologic malignancy require ongoing health care and whether these needs change with increasing time after transplantation. * Correlate physical capabilities, body image, physical limitations, including sexuality issues which alter or influence lifestyle, with time after transplantation in these patients. * Determine whether cognitive abilities relative to memory and neurobehavioral ratings change with increasing time after transplantation in these patients. * Correlate social and relationship abilities with length of time after transplantation in these patients. OUTLINE: Patients and siblings complete a self-report quality of life questionnaire, including outcome assessments of neuroendocrine function, cognitive abilities, physical capability, and psychosocial behavior. PROJECTED ACCRUAL: Approximately 750 patients (375 adult cancer survivors \[case group\] and 375 siblings \[control group\]) will be accrued for this study within 7 years.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Fred Hutchinson Cancer Research Center, Seattle, Washington, United States
Name: Jean E. Sanders, MD
Affiliation: Fred Hutchinson Cancer Center
Role: PRINCIPAL_INVESTIGATOR