Spots Global Cancer Trial Database for MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing
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Trial Identification
Brief Title: MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing
Official Title: Matched Unrelated Donor and Partially Matched Related Donor Peripheral Stem Cell Transplantation With Alpha/Beta T-Cell and B-Cell Depletion for Patients With Hematologic Malignancies With Targeted ATG Dosing Pilot Study, IDE 13641
Study ID: NCT05794880
Conditions
Interventions
Study Description
Brief Summary: This is a single arm pilot study for patients with hematologic malignancies receiving unrelated or haploidentical related mobilized peripheral stem cells (PSCs) using the CliniMACS system for alpha/beta T cell depletion plus CD19+ B cell depletion with individualized ALC-based dosing of ATG to study impact on engraftment, GVHD, and disease free survival
Detailed Description:
Keywords
Eligibility
Minimum Age: 0 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Children's Wisconsin, Milwaukee, Wisconsin, United States
Contact Details
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