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Brief Title: Safety Study of CAT-8015 Immunoxin in Patients With NHL With Advance Disease
Official Title: A Phase 1, Multicenter, Dose Escalation Study of CAT-8015 in Patients With Relapsed or Refractory Non-Hodgkin'd Lymphoma (NHL)
Study ID: NCT00515892
Brief Summary: RATIONALE: The CAT-8015 immunotoxin can bind tumor cells and kill them without harming normal cells. This may be effective treatment for Non-Hodgkin's lymphoma (NHL) that has not responded to chemotherapy, surgery or radiation therapy. PURPOSE: Phase 1 dose escalation study to determine the maximum tolerated dose of CAT-8015 immunotoxin in treating patients who have Non-Hodgkin's lymphoma and do not respond to treatment.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Tower Hematology Oncology Medical Group, Beverly Hills, California, United States
Warren Grant Megnuson Clinical Center - NCI Clinical Trials Referral Office, Bethesda, Maryland, United States
Klinika Hamtologii Uniwersytetu Medycznego (Medical University of Lodz), Lodz, , Poland