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Brief Title: Observational Study of Biomarker During Liver Surgery
Official Title: Autophagy in Liver Injury: Changes in Autophagy Biomarkers During Liver Surgery
Study ID: NCT02102971
Brief Summary: The investigators would like to study whether Sirtuin 1 (SIRT1) plays a cytoprotective role in liver ischemia/reperfusion, and ultimately to develop therapeutic strategies to improve hepatic function of patients with liver diseases.
Detailed Description: If asked to participate in this research study, it is because a liver resection/liver transplantation surgery has been scheduled. During the procedure a small section will be collected for additional testing of Sirtuin 1. In addition, information concerning the liver disease, laboratory and pathology results after surgery will be collected by the investigators.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UF Health, Gainesville, Florida, United States
Name: Jae-Sung Kim, PhD
Affiliation: University of Florida
Role: PRINCIPAL_INVESTIGATOR