Spots Global Cancer Trial Database for Diagnosis of Nodules ≤2 cm Based on US and CEUS Compared With Current Clinical Procedure
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Trial Identification
Brief Title: Diagnosis of Nodules ≤2 cm Based on US and CEUS Compared With Current Clinical Procedure
Official Title: Screening and Diagnosis of Nodules ≤2 cm in High-risk HCC Patients in China Based on US and CEUS: a Multicenter, Prospective, Randomized Controlled Study
Study ID: NCT05360420
Interventions
Study Description
Brief Summary: Due to different etiologies, diagnosis and treatment of HCC in China is different from that in Western countries.US is an important screening method for HCC in patients with liver cirrhosis. CEUS, as an enhanced imaging method based on US, has the advantages of convenience, non-radiation, low cost, short examination time, and the diagnostic performance of HCC is comparable to that of CECT, CEMRI, and hepatobiliary-specific MRI. It is of great significance to consider the cost-effectiveness of each examination based on the principle of cost minimization. Therefore, we propose immediate CEUS examination for suspicious lesions ≤2 cm screened by US, and determine the diagnostic process of further diagnostic methods based on the CEUS results. The aim of this study is to establish a screening and diagnosis process for HCC ≤2 cm suitable for China considering time effect, economic effect and diagnostic efficiency.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Tianjin Third Central Hospital, Tianjin, Tianjin, China
Contact Details
Name: Xiang Jing, MD
Affiliation: Tianjin Third Central Hospital
Role: STUDY_DIRECTOR
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