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Brief Title: Sorafenib Plus Doxorubicin Versus Sorafenib Alone for the Treatment of Advanced Hepatocellular Carcinoma: a Randomized Phase II Trial
Official Title: Sorafenib Plus Doxorubicin Versus Sorafenib Alone for the Treatment of Advanced Hepatocellular Carcinoma: a Randomized Phase II Trial
Study ID: NCT01272557
Brief Summary: This study is a prospective, randomized, open-label, multicenter phase IIB trial in order to determine time to progression of the combination therapy sorafenib plus doxorubicin against standard-of-care sorafenib in advanced HCC not amenable to non-systemic treatment.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Medizinische Klinik und Poliklinik, Heinrich-Heine-Universität, Düsseldorf, , Germany
Martin-Luther-University Halle-Wittenberg, Halle (Saale), , Germany
Universitätsklinikum des Saarlande, Homburg/Saar, , Germany
Ortenau Klinikum Lahr-Ettenheim, Lahr, , Germany
Universitätsklinikum Leipzig, Leipzig, , Germany
Klinikum Ludwigsburg, Ludwigsburg, , Germany