Spots Global Cancer Trial Database for Radioactive Holmium Microspheres for the Treatment of Unresectable Liver Metastases
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Trial Identification
Brief Title: Radioactive Holmium Microspheres for the Treatment of Unresectable Liver Metastases
Official Title: Radioactive Holmium Microspheres for the Treatment of Patients With Unresectable Liver Metastases; a Single Center, Interventional, Non-randomized, Phase II (HEPAR II) Trial
Study ID: NCT01612325
Conditions
Interventions
Study Description
Brief Summary: Radioembolisation is a known method for the treatment of liver tumors and or livermetastases. Currently small beadlets called microspheres are used that are loaded with the beta radiation emitting Yttrium-90. Holmium-166 microspheres have different physical characteristics including good visualisation in gammacameras due to the gamma emission. Because of the higher specific activity higher radiation doses to the liver will be used compared to the standard Yttrium treatment. It is hypothesized that higher doses of irradiation have an improved antitumor effect.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Department of Radiology University Medical Center Utrecht, Utrecht, , Netherlands
Contact Details
Name: Bernard Zonnenberg, MD, PhD
Affiliation: UMCU Utrecht Netherlands
Role: PRINCIPAL_INVESTIGATOR
Name: Martin Hendriks, MD, PhD
Affiliation: UMCU Utrecht, Netherlands
Role: STUDY_DIRECTOR
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