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Spots Global Cancer Trial Database for Laparoscopic Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

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Trial Identification

Brief Title: Laparoscopic Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

Official Title: Laparoscopic Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy

Study ID: NCT02203409

Conditions

Liver Tumor

Interventions

Laparoscopic ALPPS

Study Description

Brief Summary: The purpose of this research is evaluate the results with laparoscopic ALPPS procedure in a single center. The validity, feasibility and limitations were assessed objectively through our clinical prospective study.The investigators expect laparoscopic ALPPS is safe, effective and feasible.

Detailed Description: Background: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a breakthrough in the field of hepatobiliary surgery in recent years,which stimulates the remnant liver volume(RLV) grew by 74%-87.2% in 9 to 13 days。The published literature reported that the two stages of ALPPS are the conventional laparotomy surgery,Patients need to undergo the injury of two open operations in a short time. The incidence of postoperative complications and mortality rate is as high as 53% -73% and 12%-27%.The aim of this study was to evaluate the results with laparoscopic ALPPS procedure in a single center, with special emphasis in validity, feasibility and limitations. Results: Clinical data include: operation time, intraoperative blood loss, volume of blood transfusion, complications and mortality, postoperative liver function, long-term curative effect and survival time were collected and analysed. Statistical method:groups t-test ,univariate/multivariate analysis, logistic regression analysis, mixed linear regression, Cox survival analysis ,Kaplan-Meier survival analysis,Log-rank survival curves were used.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Southwest Hospital, Chongqing, , China

Contact Details

Name: Shuguo Zheng

Affiliation: Institute of Hepatobiliary Surgery ,Southwest Hospital ,Third Military Medical University

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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