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Brief Title: ALLPS VERSUS PVO Randomized Controlled Trial
Official Title: ASSOCIATING LIVER PARTITION WITH PORTAL VEIN LIGATION FOR STAGED HEPATECTOMY (ALPPS) Versus Conventional Portal Vein Occlusion (PVO) for Resection of Liver Tumors Unresectable in One Step - a Randomized Controlled Trial
Study ID: NCT01775267
Brief Summary: This randomized phase II trial compares how well associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) or portal vein occlusion (PVO) works in treating patients with liver cancer. Both treatments are types of 2-stage hepatectomies for removing liver cancer. ALPPS may be more effective than PVO in patients whose disease would traditionally be considered inoperable. * Trial with surgical intervention
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Washington University, St. Louis, Missouri, United States
Italian Hospital, Department of Surgery, Division of HPB surgery and Liver Transplatn Unit, Buenos Aires, , Argentina
University Hospital Zurich, Division of Visceral and Transplant Surgery, Zurich, ZH, Switzerland